Systematic engineering of TROP2-targeted CAR T-cell therapy overcomes resistance pathways in solid tumors.

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Brea EJ, Baldacci S, Savage N, et al. Cancer Immunol Res. 2025;13(11):1749–1763. doi:10.1158/2326-6066.CIR-25-0527.

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Systematic engineering of TROP2-targeted CAR T-cell therapy overcomes resistance pathways in solid tumors.
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